Job Postings
Principal Researcher, DMPK
Company Eisai, Inc.
Location Andover, MA
Job Title Principal Researcher, DMPK
Job Type Full Time
   
To apply: Click here

Job Description:
Responsible for bioanalysis of drug development and clinical projects. The primary role of the Principal Researcher is to develop and validate LC-MS/MS methods, perform sample analysis, and data tabulation for pharmacokinetic (PK) and toxicokinetic (TK) studies. The duties also include preparation of method validation protocols and study reports, presentation of analytical and PK/TK results to project teams, and compiling analytical reports for regulatory submissions. The results generated may have direct or indirect impact on projects advancement/discontinuation.

Responsibilities include but are not limited to::
  • Operate LC-MS/MS instruments efficiently and conduct routine troubleshooting independently
  • Develop and validate LC-MS/MS and/or ELISA methods for new chemical and biological entities
  • Develop scientifically-sound assays independently, based on existing or literature procedures
  • Analyze samples for pharmacokinetics and toxicokinetics to support milestone achievement of projects at various stages of drug development
  • Maintain laboratory equipment, and train others in its use.
  • Communicate effectively with project teams to ensure reliable and efficient delivery of analytical and PK results. Participate in research group discussion and project meetings.
  • Communicate research results to supervisor in a timely manner
  • Utilize literature searches to solve specific research and assay development issues independently
Job Qualifications:
  • B.S. (5-7 years experience) or M.S. (3-5 years experience) in Analytical Chemistry/Biology, Pharmaceutical Sciences.
  • Excellent analytical skills, specifically in LC-MS/MS and/or ELISA.
  • Familiar with regulatory requirement for method validation.
  • Good knowledge in pharmacokinetics concepts.
  • Experience in software for lab information management and pharmacokinetic analysis, such as Watson and WinNonlin.
  • Good time management skills and capable of independently design efficient and well-controlled experiments.
  • Good communication and presentation skills
  • Limited Travel: Less than 5% to attend meetings and conferences, etc