Job Postings
Nulabel Technologies
SENIOR INVESTIGATOR - Force Field Development
 

Position Description:
Silicon Therapeutics, a Boston-based integrated computational drug discovery company, is looking for a computational scientist with expertise in developing molecular dynamics and free energy methods for drug discovery applications. Our science, our team, and our mission are focused on applying advanced computational technologies to build and progress a pipeline of innovative medicines for patients. We recently finalized our series A financing and are building a team of outstanding individuals to continue developing our INSITE platform. Competitive pay, equity, strong perks, and a fun working environment, along with a desire to do cutting edge science to design better medicines, are all good reasons to join us! Apply or learn more at www.silicontx.com. Please find the job description below:

Responsibilities:
  • Develop a robust solution for generating high-quality force field parameters for drug-like molecules
  • Develop workflows to integrate the force field into drug discovery applications
  • Investigate the latest trends and scientific advancements in the field and help assess what should be brought into the Silicon Tx INSITE platform
 
Required Qualifications:
  • Highly motivated to develop computational methods for discovering better medicines
  • Ph.D. in computational chemistry, physical chemistry, chemical physics, or related fields
  • Significant experience developing small molecule force fields for use in MD
  • Extensive programming experience (C/C++ and Python preferred)
  • Advanced knowledge of scientific algorithm development
  • Broad experience with statistical mechanics and thermodynamics
  • Peer-reviewed publications in relevant areas and/or demonstrated success in related development pro-jects
  • Excellent communication skills and strong team player
 
Additional Desirable Qualifications:
  • Experience with structure-based drug design methods
  • Experience working in drug discovery projects
  • Experience working with a diverse team on an ambitious project¬†
  • Experience with parallel programming (e.g. MPI, OpenMP, CUDA)

About Silicon Therapeutics
Silicon Therapeutics is an integrated computational drug discovery company focused on developing novel medicines for diseases with targets that are currently considered to be challenging for traditional approaches. Our INSITE platform closely represents the real dynamical nature of targets using accurate all-atom simulations, enabling us to design and optimize compounds for targets that were previously considered "undruggable." Our science, our team, and our mission are focused on applying advanced computational technologies to build and progress a pipeline of innovative medicines for patients. Silicon Therapeutics is headquartered in Boston, MA, USA with offices in Shanghai, China. Learn more at www.silicontx.com 

 

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